Sildenafil (Viagra): A 101 Guide

Written by: Clara Hanson-Smith

Reviewed by: Sunny Dhain MPharmRS PgDip IndP

Date reviewed: 06/03/2024

Sildenafil treats ED in men, a condition that is characterised by the difficulty in achieving or maintaining an erection. The treatment works by relaxing smooth muscles in the penile blood vessels. This relaxation allows increased blood flow during sexual arousal, helping to achieve and sustain an erection.

Sildenafil effectiveness

Sildenafil has proven effective in treating ED in many clinical studies. It works by increasing blood flow to the penis when sexually aroused helping to achieve and maintain an erection. However, Sildenafil is not an aphrodisiac and requires sexual stimulation to be effective. Its effectiveness varies, and it may not suit everyone, especially those with certain medical conditions or on specific medications. The Family Chemist’s pharmacists can guide patients on appropriate dosage and usage.

Sildenafil Onset Time

Studies show that sildenafil’s onset time varies from 30 minutes to 1 hour to start working after it has been taken. However, the onset time can vary from person to person. Factors that can influence how quickly Sildenafil begins to work include:

1. Metabolism

Individual metabolic rates can affect how quickly the body processes the medication.

2. Food intake

Taking Sildenafil on an empty stomach can lead to faster absorption, meaning it may work quicker. If taken after a heavy or high-fat meal, it may take longer for Sildenafil to start working.

3. Level of sexual arousal

Sildenafil requires sexual stimulation to be effective. The level of arousal can play a role in how quickly the medication starts working.

Maximizing sildenafil effectiveness

There are several strategies you can consider to optimise the duration of Sildenafil’s effectiveness. However, it’s important to note that while these tips can help maximize the medication’s potential, they don’t extend the inherent active period of Sildenafil, which typically lasts about 4 to 6 hours. Here are some tips:

✅ Proper timing

Take sildenafil about 1 hour before sexual activity. This timing allows the medication to reach its peak concentration in your bloodstream when you’re most likely to need it.

✅ Avoid heavy meals

Taking Sildenafil on an empty stomach can help it work more quickly and effectively. Heavy or fatty meals can delay the absorption of Sildenafil, potentially shortening its period of effectiveness during your time of need.

✅ Limit alcohol consumption

Alcohol can impair your ability to get an erection. Moderate to heavy alcohol use can also interfere with the effectiveness of sildenafil.

✅ Stay relaxed and stress-free

Anxiety and stress can impact erectile function and the effectiveness of sildenafil. Being relaxed can enhance the medication’s effectiveness.

✅ Ensure adequate sexual stimulation

sildenafil requires sexual arousal to work. Engage in adequate foreplay or whatever stimulates you sexually.

✅ Manage your overall health

Chronic health conditions like diabetes, heart disease, and high cholesterol can affect the duration and effectiveness of sildenafil. Managing these conditions through lifestyle changes and medication can improve the drug’s effectiveness.

Duration of Sildenafil effects

Sildenafil’s effects typically last 4 to 6 hours. Its duration varies per individual and depends on factors like metabolism, health, and dosage. It does not permanently affect erectile function or cure ED.

Sildenafil’s side effects

Common side effects include:

• Headaches
• Flushing
• Indigestion
• Nasal congestion
• Visual changes
• Dizziness
• Muscle aches

Rare side effects include:

• Priapism
• Heart-related issues

Alternatives to Sildenafil

Several alternatives to sildenafil are available for the treatment of erectile dysfunction (ED). Treatment choice depends on individual preferences, the underlying causes of ED, and any specific medical conditions. Here are some common alternatives:

2. Tadalafil (Cialis)

Cialis, containing tadalafil, is another widely used medication for ED. It has a longer duration of action compared to sildenafil, with effects lasting up to 36 hours. This allows for greater flexibility in the timing of sexual activity.

3. Vardenafil (Levitra)

Levitra, which contains vardenafil, is like sildenafil’s mechanism of action. It can be effective in treating ED and is available in different doses.

4. Avanafil (Spedra)

Spedra, or avanafil, is a newer medication for ED. It has a rapid onset of action and can work in as little as 15 minutes in some individuals.

5. Vacuum Erection Devices (VEDs)

VEDs are non-invasive devices that create a vacuum to draw blood into the penis, producing an erection. They can be used as an alternative or in combination with medications.

7. Lifestyle Changes

For some individuals, making lifestyle changes such as improving diet, increasing physical activity, quitting smoking, and managing stress can help alleviate ED.

9. Herbal and natural remedies

Some people explore herbal supplements and natural remedies for ED, but their effectiveness and safety can vary. It’s essential to consult with a healthcare provider before trying such options.

Sildenafil FAQs