PLEASE NOTE: WE DO NOT SUPPLY NEEDLES, SWABS AND SHARPS BIN WITH THE PENS. THESE WILL NEED TO BE PURCHASED SEPARATELY. OR PLEASE PURCHASE THE MOUNJARO 2.5MG STARTER PACK.
Buy Mounjaro online from The Family Chemist
Mounjaro is an innovative injectable treatment for weight management, using tirzepatide to mimic hormones that regulate appetite and glucose levels. It’s designed for adults with obesity or overweight issues, aiming to enhance fullness from less food. When combined with a healthy diet and exercise, Mounjaro offers a sustainable approach to weight loss. This dual-action mechanism targets both appetite control and blood sugar management.
Why choose The Family Chemist?
- A FREE weight management plan. FREE video calls with The Family Chemist clinician.
- Aftersales support and follow-up to ensure you are confident with Mounjaro.
- GPhC and MHRA registered Pharmacy with UK clinicians.
- 24-hour delivery without the need to see your GP or Pharmacy.
Please Note: This item can only be delivered using next day delivery. Next day delivery ensures you receive your parcel into your hands instead of leaving it outside your door or behind a bin. Delivery must be accepted on the first delivery attempt to maintain the cold chain. This is a temperature-controlled item and will be sent with ice packs and a temperature-controlled pouch.
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Pricing
| Mounjaro Injection Pen | |
2.5mg Starter Pack: Needles, swabs & sharpsbin | £166.93 |
| 2.5mg | £149 |
| 5mg | £149 |
| 7.5mg | £169 |
| 10mg | £169 |
| 12.5mg | £185 |
| 15mg | £185 |
When starting the consultation you will be redirected to the treatments page where you can start the short questionnaire.
Same day dispatch if ordered before 2pm
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Mounjaro FAQs
Buy Mounjaro Online
Harness the power of tirzepatide, a cutting-edge solution designed to control appetite and improve glucose levels, all from the comfort of your home. Trust in The Family Chemist to support your journey towards a sustainable, healthier weight with Mounjaro, a revolutionary step in overcoming obesity and overweight challenges. Begin your path to wellness today.
What Is Mounjaro
Mounjaro is an innovative weight loss injection, the latest in the line of GLP1 receptor agonists, specifically designed for individuals with a body mass index (BMI) of over 30. Its active ingredient, tirzepatide, is at the heart of Mounjaro’s effectiveness, providing a scientifically backed method to assist in weight reduction efforts.
Mounjaro functions by mimicking the action of hormones that target areas of the brain involved in appetite regulation. By administering a once-weekly injection under the skin, Mounjaro aids in significantly reducing food cravings and promoting feelings of fullness. Clinical trials have demonstrated Mounjaro’s ability to help individuals achieve an impressive ~20% reduction in body weight, marking it as a highly effective option for weight loss.
This cutting-edge treatment is available through our UK-registered online prescribing service, ensuring a convenient and secure route to commence your weight loss journey. After completing a straightforward online assessment with our team of clinicians, eligible individuals can have their prescriptions swiftly processed and delivered in 24 hours. Our dedicated pharmacy team then prepares and dispatches the treatment directly to you, ensuring a seamless transition to a healthier lifestyle.
How Does Mounjaro Work?
The Science Behind Mounjaro
Mounjaro, containing the active ingredient tirzepatide, is a once-weekly injectable peptide that operates on a novel principle by targeting not one, but two key receptors involved in metabolic regulation: the glucagon-like peptide-1 (GLP-1) receptor and the glucose-dependent insulinotropic polypeptide (GIP) receptor.
Dual Receptor Agonism: A Two-Pronged Approach
Tirzepatide’s dual action is at the core of its effectiveness. By acting as an agonist for both GIP and GLP-1 receptors, Mounjaro taps into the body’s own mechanisms for regulating appetite and energy balance. GIP plays a critical role in managing energy balance through its action on brain and adipose tissue receptors, contributing to a regulation of food intake and energy expenditure. The GLP-1 receptor’s involvement in insulin secretion and appetite regulation further complements this action, leading to a more comprehensive approach to weight management.
Clinical Trials and Efficacy
The SURMOUNT-1 trial, among others, has provided compelling evidence of Mounjaro’s efficacy in weight management. Participants without diabetes but with obesity or overweight status experienced significant weight reduction, underscoring the potential of this dual-agonist approach. These trials have not only confirmed the weight loss capabilities of tirzepatide but also highlighted its safety profile, making it a promising option for those eligible.
Molecular Mechanisms at Play
Mounjaro’s molecular mode of action is fascinating. The peptide is engineered from the native GIP sequence to precisely target the GIP and GLP-1 receptors. Its affinity for the GIP receptor is comparable to that of native GIP, while its binding to the GLP-1 receptor, although slightly weaker, is sufficiently potent to activate the receptor’s weight loss mechanisms. This dual receptor activation is thought to synergize, enhancing the weight loss effect beyond what could be achieved through GLP-1 receptor activation alone.
The GIP component is believed to act centrally, augmenting the weight loss induced by GLP-1, while also targeting white adipose tissue to improve lipid storage and prevent dietary lipid spillover. This mechanism is crucial for managing the body’s energy and lipid metabolism, offering a protective effect against the accumulation of excess body fat.
How Long Does It Take For Mounjaro To Work?
The full impact of Mounjaro, particularly in the context of weight management, might take several weeks to become evident. This gradual unveiling of its efficacy is partly due to the methodical escalation of the dosage over time, which aims to minimize potential side effects for the patient.
For those seeking weight loss, the research underscores the significant potential of Mounjaro. Specifically, individuals on the highest dosage, 15mg, witnessed remarkable weight reductions, with some losing up to 22.5% of their initial body weight. Optimal results are achieved when Mounjaro is complemented by a healthy lifestyle, including a balanced diet, minimal snacking between meals, and consistent physical activity, ideally totalling 150 minutes per week.
This efficacy is backed by robust clinical trials. The phase 3 multicenter, double-blind, randomized, placebo-controlled trial, involving 119 sites across nine countries, highlighted Mounjaro’s superior performance over placebo in substantial weight loss among participants. Over a 72-week treatment period, which included a comprehensive lifestyle intervention, participants on tirzepatide experienced significant weight reductions—15.0%, 19.5%, and 20.9% for the 5mg, 10mg, and 15mg doses, respectively, compared to a 3.1% reduction with placebo.
Moreover, the study revealed that beyond weight loss, Mounjaro offers additional health benefits. These include improvements in waist circumference, blood pressure, fasting insulin levels, and lipid profiles, among others. Such changes underscore the potential for Mounjaro not just in weight management but also in mitigating risks associated with cardiovascular diseases and other metabolic disorders.
In terms of safety, while the majority of participants experienced at least one adverse event, these were predominantly gastrointestinal in nature, mild to moderate in severity, and mostly occurred during the dose-escalation phase. This indicates that while Mounjaro is highly effective in promoting weight loss and improving metabolic health, it is also accompanied by a manageable safety profile.
How Do I Use Mounjaro?
Mounjaro® is available in multiple dosages: 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg solutions for injection, each supplied in one pre-filled pen designed for easy use. Before using Mounjaro®, always read the instructions for use and the package leaflet provided with your pen for the latest information and guidance.
Mounjaro Dosage and Administration
- Initial Phase: Start with 2.5 mg once weekly for the first four weeks.
- Titration: Increase the dose in 2.5 mg increments every 4 weeks as advised, up to a maintenance dose of 5 mg, 10 mg, or 15 mg weekly, depending on tolerance and response.
How to Inject Mounjaro
- Timing: Administer Mounjaro once a week, ideally on the same day and time, to maintain steady medication levels.
- Injection Sites: Inject into the abdomen, upper thighs, or outer section of the upper arms. Avoid veins and muscles. Rotate injection sites within these areas to reduce irritation.
- Preparation: Use a new needle for each injection. Inspect your pen and needle for damage and ensure the medication is clear and colourless to slightly yellowish.
- Dosing Schedule: Begin with a 2.5 mg dose once a week for 4 weeks, then increase the dose as directed, following a titration schedule to optimize efficacy and minimize side effects.
Preparing for Injection
- Storage and Handling: Keep your pen refrigerated. Before use, inspect the pen to ensure it’s not damaged and that the medication inside is not frozen, cloudy, or discolored.
- Selecting an Injection Site: Mounjaro® should be injected subcutaneously into the abdomen, thigh, or upper arm. It’s crucial to rotate the injection site each week to prevent tissue irritation.
- Preparing the Pen: Wash your hands thoroughly. Check the pen’s label for the correct medicine, dose, and expiration date. Remove the grey base cap only when you’re ready to inject.
Troubleshooting Mounjara
- Air Bubbles: Normal in the pen and do not affect the dose.
- Room Temperature: There’s no need to warm the pen before use.
- Post-Injection Leakage: A drop of liquid or blood on the skin post-injection is normal. Apply gentle pressure with a cotton ball or gauze without rubbing the site.
Key Considerations For Mounjara
- Food and Timing: Mounjaro can be taken with or without food. The time of day for injection doesn’t impact its effectiveness, but consistency in the timing of doses does.
- Long-Term Use: It’s safe for long-term treatment. Continue as advised by The Family Chemist clinician until you achieve your weight loss goals or as long as it’s effective and tolerable for diabetes management.
- Missed Doses: If you miss a dose, take it as soon as you remember within 4 days. If it’s been more than 4 days, skip the missed dose and return to your regular schedule without doubling up.
- Changing Schedule: You can change the day of your weekly injection if needed, ensuring there’s at least a 3-day gap between doses.
Disposal and Safety
- Each pen should be disposed of properly in a sharps bin after administration.
- Always use a new needle for each injection to prevent infection and ensure sterility.
Monitoring and Adjustments
- Monitor your body’s response to Mounjaro. Adjustments to the dosage may be necessary based on effectiveness and side effects.
- If adding Mounjaro to other diabetes medications like sulphonylureas or insulin, monitoring and dose adjustments may be needed to reduce the risk of hypoglycemia
Who Cannot Use Mounjaro?
Mounjaro may not be suitable for all patients. The following patients with comorbidities should not use Mounjara or use with caution:
Acute Pancreatitis
Patients with a history of pancreatitis must exercise caution with Mounjaro, as tirzepatide has not been extensively studied in this population. If symptoms of acute pancreatitis appear, the use of tirzepatide must be immediately halted. Tirzepatide is contraindicated if acute pancreatitis is diagnosed, underscoring the importance of patient education on recognizing these symptoms.
Hypoglycemia Risk
Tirzepatide, when used alongside insulin or sulphonylureas, increases the risk of hypoglycemia. It may necessitate a dosage adjustment of insulin or sulphonylurea drugs. Patients require careful monitoring to manage this risk effectively, highlighting the need for professional oversight in adjusting treatment plans.
Gastrointestinal Side Effects
The occurrence of nausea, vomiting, and diarrhea as side effects may lead to dehydration and potentially acute renal failure. Such risks are especially pertinent for elderly patients, who are more prone to complications. The emphasis is on preventive measures to maintain adequate hydration and electrolyte levels.
Severe Gastrointestinal Disease
Mounjaro is contraindicated for patients with severe gastrointestinal diseases, such as significant gastroparesis, due to the absence of relevant studies. This highlights the necessity for caution and thorough patient evaluation before considering tirzepatide as a treatment option.
Diabetic Retinopathy
Patients with specific forms of diabetic retinopathy should not use Mounjaro.
Elderly Patients
The use of Mounjaro in patients over 85 years old is contraindicated.
Drug Interactions
Tirzepatide’s effect on the absorption rates of orally administered medications necessitates close monitoring, particularly for drugs with a narrow therapeutic index. This requirement underscores the importance of healthcare provider involvement in monitoring and adjusting medications as needed.
Special Populations
- Pregnancy: Mounjaro is contraindicated for use during pregnancy or for women planning to become pregnant.
- Breastfeeding: Given the unknowns regarding tirzepatide’s excretion in human milk, it cannot be used by breastfeeding women.
What are the Side Effects of Mounjaro?
What Are the Most Common Side Effects of Mounjaro?
When starting Mounjaro for weight loss or diabetes management, many people experience very common side effects including diarrhea, nausea, vomiting, constipation, and low blood sugar, particularly when taken with certain diabetes medications. These symptoms are typically mild and tend to decrease over the first few weeks of treatment.
Can Mounjaro Cause Low Blood Sugar?
Yes, Mounjaro can lead to low blood sugar levels, especially when used in combination with other diabetes medications like insulin. Symptoms of low blood sugar include shaking, sweating, dizziness, hunger, and a rapid heartbeat. It’s crucial to inform your doctor if you experience these symptoms.
What Are Other Common Side Effects of Mounjaro?
Besides the very common side effects, Mounjaro users may also encounter a fast pulse, allergic reactions like eczema or itching, stomach pain, indigestion, bloating, gas, heartburn, fatigue, increased pancreatic enzymes, irritation at the injection site, low blood pressure, dizziness, and hair loss.
Are There Any Uncommon Side Effects of Mounjaro?
Uncommon side effects include gallstones, an increase in calcitonin levels, weight loss, pain at the injection site, and acute pancreatitis. If you experience severe stomach and back pain, indicating pancreatitis, seek immediate medical assistance.
Does Mounjaro Have Any Long-Term Side Effects?
Mounjaro is not known to cause long-term side effects. Most side effects are transient and improve within a few weeks or upon discontinuation of the medication.
What Should I Do If I Experience Serious Side Effects From Mounjaro?
Mounjaro can cause serious allergic reactions (anaphylaxis) and acute pancreatitis, which are medical emergencies. Symptoms like breathing difficulties, swelling of the throat, face, and mouth, fainting, severe stomach and back pain require immediate medical attention by calling emergency services or visiting an emergency department.
How Can I Manage Side Effects From Mounjaro?
To mitigate side effects, take Mounjaro consistently each week, manage nausea with cold water and smaller, non-greasy meals, consume adequate fiber, stay hydrated, and use anti-diarrhea medicine if necessary. Always follow your doctor’s prescribed dosage and report any persistent or bothersome side effects.
By formatting the information into questions commonly searched by users, the content is made more accessible and helpful to individuals seeking to understand the side effects associated with Mounjaro.
What are the Alternative to Mounjaro?
Weight Loss Treatment Comparison
| Category | Medication | Active Ingredient(s) | Mode of Action | Administration | Dosage | Weight Loss % | Common Side Effects | Manufacturer | Note |
|---|---|---|---|---|---|---|---|---|---|
| Injection | Mounjaro | Tirzepatide | GLP-1 receptor agonist and GIP mimetic | Once weekly | Starting at 2.5mg, up to 15mg | Up to 21% to 22.5% | Nausea, indigestion, diarrhea, vomiting, constipation, stomach pain | Eli Lilly | Significant weight loss efficacy |
| Injection | Wegovy | Semaglutide | GLP-1 receptor agonist | Once weekly | Starting at 0.25mg up to 2.4mg | About 15% | Nausea, indigestion, diarrhea, vomiting, constipation, stomach pain | Novo Nordisk | MHRA approved for weight loss |
| Injection | Saxenda | Liraglutide | GLP-1 receptor agonist | Once daily | Starting at 0.6mg up to 3mg | About 5% to 10% | Nausea, hypoglycemia, diarrhea, constipation, headache, decreased appetite | Novo Nordisk | MHRA Approved |
| Tablet | Xenical | Orlistat | Lipase inhibitor | With meals | One up to three times a day | About 5% to 10% | Oily spotting, gas with discharge, fecal urgency, fatty/oily stool | Haleon | Prevents fat digestion |
| Tablet | Orlistat (generic) | Orlistat | Lipase inhibitor | With meals | One up to three times a day | About 5% to 10% | Similar to Xenical: Oily spotting, gas, fecal urgency | Generic | Unbranded version of Xenical |
| Tablet | Alli | Orlistat | Lipase inhibitor | With meals | 60mg up to three times a day | About 5% | Similar to Xenical but may be milder due to lower dose | Not specified | Over-the-counter option |
| Tablet | Mysimba | Bupropion and Naltrexone hydrochloride | Multimodal action | With meals | One to four tablets a day | About 5% to 10% | Nausea, constipation, headache, dry mouth, dizziness | Not specified | Acts on brain to control hunger |
Is Mounjaro More Effective Than Wegovy?
Does Mounjaro interact with the Contraceptive Pil?
Research shows that taking a single dose of tirzepatide can slightly reduce the effectiveness of your oral contraceptive. Specifically, the peak concentration (Cmax) and the overall exposure (AUC, which measures how much of the drug is in your bloodstream over time) of the hormones in your birth control pill are decreased.
What comes with my Mounjaro order?
Your Mounjaro order will arrive with simply just the Mounjaro pen. You will need to purchase needles for injecting, alcohol pads and sharps bin separately. You can read more about using your Mounjaro pen by reading the patient information leaflet here.
What do I get with the Starter Pack?
Starter Pack
1. Mounjaro Pen 2.5mg (4 weeks)
2. 100 x GlucoRx Needles
3. 100 x Alcohol Swabs
4. 1 x Sharpsbin
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