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Buy Zyban the safe and easy way without visiting your GP or pharmacy.



60 Tablets

120 Tablets



Zyban tablets
You can select from the quantities after filling out the short online consultation.
Same day dispatch if ordered before 2pm
Discreet and plain packaging
Free expert support & advice
Consult a doctor

Frequently asked questions

Zyban is a medicine prescribed to help you stop smoking. Zyban is a prescription only medicine with an active ingredient called Bupropion 150mg modified release tablets. This is a nicotine free quit aid. Zyban reduces interest in smoking, the cravings and withdrawal symptoms. The medication will be most effective if you are fully committed to giving up smoking.

Bupropion has been used in the past for other purposes but we at The Family Chemist only prescribe Zyban to help patients stop smoking.

Buproprion was first developed to treat depression but it was found that it helps patients give up smoking. It is not clear how it works but it is thought to alter the level of transmitters in the brain.

A cigarette contains nicotine which is a highly addictive chemical. Nicotine promotes the release of dopamine in the brain. Dopamine (“happy hormones”)is part of your reward system and gives you a sense of pleasure and motivation to continue smoking. When you stop smoking the brain releases transmitters which cause typical withdrawal symptoms such as craving, feeling anxious, restlessness, headaches, or irritability. Zyban acts to reduce the withdrawal symptoms by controlling the release of transmitters in the brain. Your brain gets less reward from smoking, so it becomes easier to quit.

Whilst this medicine was developed as an antidepressant, you do not need to be diagnosed with depression for it to work as a quit smoking aid. Although if you do develop quit related mood changes zyban may help offset the symptoms.

How effective is Zyban?

Zyban does increase the chances of quitting smoking. Many studies have looked at this issue. The studies found that twice the number of smokers who take bupropion stop smoking compared to those who don’t take bupropion.

When to start and how much to take
Start taking Zyban while you are still smoking

Set a target stop smoking day ideally during the second week you’re taking it
Week 1
Ideally keep smoking while taking Zyban
Days 1 to 6
Day 7
Take one tablet (150mg) once a day
Increase your dose to one tablet twice a day at least 8 hours apart
and not near to bedtime.
Week 2 Carry on taking one tablet twice a day
Stop smoking this week on you Target Stop Smoking Day
Weeks 3 to 9 Carry on taking one tablet twice a day for up to 9 weeks.
If you have not been able to stop smoking after 7 weeks you need to stop taking Zyban
You may stop taking Zyban gradually after 7-9 weeks.

Don’t take Zyban:

  • if you are allergic to bupropion or any of the other ingredients of this medicine.
  • if you are taking any other medicines which contain bupropion
  • if you have a condition that causes fits (seizures), such as epilepsy, or if you have a history of fits
  • if you have an eating disorder or had one in the past (for example, bulimia or anorexia nervosa)
  • if you have severe liver problems, such as cirrhosis
  • if you have a brain tumour
  • if you are usually a heavy drinker and you have just stopped drinking alcohol, or are going to stop while you’re taking Zyban
  • if you have recently stopped taking sedatives or medicines to treat anxiety (especially benzodiazepines or similar medicines), or if you are going to stop them while you’re taking Zyban
  • if you have a bipolar disorder (extreme mood swings) as Zyban could bring on an episode of this illness
  • if you are taking medicines for depression or Parkinson’s disease called monoamine oxidase inhibitors (MAOIs) or have taken them in the last 14 days. The timing may be shorter for some types of MAOIs, your doctor will advise you.

Warnings and Precautions

Fits (seizures)

Zyban has been shown to cause fits (seizures) in about 1 in 1,000 people

Fits are more likely:

  • if you regularly drink a lot of alcohol
  • if you have diabetes for which you use insulin or tablets
  • if you have had a serious head injury or a history of head trauma.

If you have a fit (seizure) during treatment: Stop taking Zyban and don’t take any more. See your doctor.

You may have more risk of side effects:

  • if you have kidney or liver problem • if you are aged over 65.

You will need to take a lower dose and be checked closely while you are taking Zyban.

If you have had any mental health problems…

Some people taking Zyban have had hallucinations or delusions (seeing, hearing or believing things that are not there), disordered thoughts or extreme mood swings. These effects are more likely in people who have had mental health problems before.

If you feel depressed or suicidal…

Some people become depressed when they try to stop smoking; very occasionally, they may think about committing suicide or try to do so. These symptoms have affected people taking Zyban, most often in the first few weeks of treatment.

If you feel depressed or think about suicide:

➔ Contact your doctor or go to a hospital straight away.

If you are taking medicines for depression… The use of these medicines together with Zyban can lead to serotonin syndrome, a potentially life threatening condition.

High blood pressure and Zyban…

Some people taking Zyban have developed high blood pressure which needs treatment. If you already have high blood pressure, it can become worse. This is more likely if you are also using nicotine patches to help you stop smoking.

You will have to check your blood pressure before you take Zyban and while you are taking it, especially if you already have high blood pressure. If your blood pressure increases, you may need to stop taking Zyban.

Zyban with alcohol

Some people find they are more sensitive to alcohol while taking Zyban. The Family Chemist clinician may suggest you do not drink alcohol while you’re taking Zyban or try to drink as little as possible. If you do drink a lot now, don’t just stop suddenly, because that may put you at risk of having a fit.

Driving and using machines

Some of the side effects of Zyban, such as feeling dizzy or light-headed, may affect your concentration and judgement. If you are affected, don’t drive, or operate machinery.

Pregnancy and Breastfeeding

Don’t take Zyban if you are pregnant, think you may be pregnant or are planning to have a baby. The ingredients of Zyban can pass into breast milk so do not breastfeed whilst using Zyban.

You may not experience any side effect at all however the most common side effects reported include dry mouth, difficulty sleeping (insomnia), headaches, feeling and being sick, constipation, dizziness.

Please refer to the patient information leaflet for a full list of the side effects, cautions and contraindications.

Yes you can buy Zyban online from The Family Chemist. The Family Chemist has gone above and beyond in ensuring we comply to all standards stipulated by the General Pharmaceutical Council, Legit Script, NPA and IPO.

We have a clinician on site who can review your consultation and generate a prescription, have it dispensed at our UK registered Pharmacy and sent out on the same day. The consultation should only take a matter of few minutes but please do answer them accurately and honestly so the clinician can make sure the Zyban is safe for you to use.

Once the consultation is approved you will receive tracking from Royal Mail and hopefully receive the parcel in less than 24 hours.

Get your prescription medication in three easy steps. I know – Simple and hassle free. Go on give us a go. You won’t be disappointed.

Complete a free quick online questionnaire for the treatment selected

Choose your preferred prescription medication

Receive your medication discreetly on the next day from our UK registered pharmacy

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