Tadalafil: When Should I Take It?
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Navigating the world of medications when it comes to erectile dysfunction (ED) can often be overwhelming. Among the array of choices, tadalafil stands out due to its unique effectiveness. But a common question asked is ‘when is the best time to take tadalafil’?
In this blog, we aim to make the world of tadalafil clearer. From timing and dosage; tadalafil should be clearer and guidance easy to follow in order to maximise its benefits. Especially when considering that timing can play a crucial role in how effective treatment can be.Â
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What is Tadalafil?
Tadalafil is a medication which falls under a class called PDE5 inhibitors, used primarily for treating erectile dysfunction (ED). They work by relaxing blood vessels and therefore improving blood flow to the penis in order to easier achieve and maintain an erection. Many people will opt for tadalafil over other medications in the same class due to its outstanding long-lasting effect, remaining active for up to 36hrs. Offering flexibility and spontaneity so your ED doesn’t get in the way of keeping in the mood.
Tadalafil can be taken either as needed (typically 10 or 20 mg) or as a lower daily dose (2.5 or 5 mg), depending on individual needs and lifestyle; all of which can be discussed with one of our clinicians. It’s effective within 30 to 60 minutes after taking.
Unfortunately, tadalafil does interact with certain medications, such as nitrates, and so isn’t suitable for everyone. Those with heart conditions such as uncontrolled blood pressure, a history of heart attacks or strokes would also find tadalafil, and other PDE5 inhibitors unsuitable. As with any new medication you might be considering, it is essential to consult with a healthcare professional before you begin taking tadalafil, and declare a complete medication history including any medication you might be taking to ensure that this medication is right for you.
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When to take Tadalafil for ED
Tadalafil, used for treating erectile dysfunction (ED), can be taken in two ways depending on an individual’s needs and the prescriber’s advice. Generally speaking, the two ways tadalafil should be taken are as follows:
1. As Needed: Tadalafil should be taken about 30 to 45 minutes before sexual activity. This is ideal for those who don’t engage in sexual activities frequently or who may not suffer from ED regularly. The effects can last up to 36 hours, offering a large window for spontaneity, as tadalafil will not work unless there is sexual stimulation.Â
2. Daily Use: For those preferring readiness at any time, a lower dose (usually 2.5 or 5 mg) can be taken every day at the same time. This ensures a consistent level of medication in your system. For those who plan to use tadalafil typically more than once a week.Â
It’s important to note that Tadalafil can be taken with or without food, and that alcohol can inhibit the effectiveness of tadalafil as well as increase potential side effects.Â
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You should stop taking Tadalafil if…
On occasion people may react to medications with severe side effects, or with an allergic reaction. In cases such as these, people are advised to stop their treatment and seek urgent medical attention. Examples of when this is necessary includes:
- Allergic reactions: If you develop symptoms of an allergic reaction, such as rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, or difficulty breathing, you should stop taking tadalafil immediately and seek emergency medical attention.
- Vision changes: Tadalafil may rarely cause blurred vision or decreased vision in one or both eyes. If you experience any changes in vision while taking tadalafil, stop using the medication and contact your doctor promptly.
- Priapism: Priapism is a prolonged and painful erection that lasts for more than four hours. Damaging not only the penis, but your general health too. While priapism is a rare side effect, in cases you should seek immediate medical attention.
- Sudden hearing loss: Some individuals may experience sudden hearing loss or ringing in the ears (tinnitus) while taking tadalafil. If you notice any changes in your hearing, stop taking tadalafil and contact your doctor.
- Severe cardiovascular symptoms: Stop taking tadalafil and seek medical help if you experience symptoms of a heart attack (such as chest pain, nausea, sweating).
- Other severe side effects: Additionally, if you develop severe side effects such as chest pain, fainting, irregular heartbeat, difficulty breathing, or swelling of the ankles, feet, or hands, you should discontinue tadalafil and seek medical attention promptly.
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Tips for taking Tadalafil
- Without food: This can be taken with or without food; however, heavy meals may delay its onset.
- Limit alcohol consumption: Limit or avoid alcohol as it can increase side effects and impair the ability to achieve an erection.
- Avoid grapefruit: Grapefruit and grapefruit juice may interact with tadalafil and lead to unwanted side effects.
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More lifestyle changes which may help with your erectile dysfunction:

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The Bottom Line
The timing for taking tadalafil varies based on its intended use and individual preferences. Whether opting for daily use or as needed, it offers a convenient and flexible approach to managing ED. Always follow the guidance of a healthcare provider and discuss any concerns or questions in order to achieve optimal results from this medication.
