Avarante (Tadalafil)

“Avarante” is an over-the-counter remedy for erectile dysfunction (ED) that can be acquired without the need for a prescription. It’s offered in a dosage of 10mg. This is the branded form of tadalafil, though available without a prescription unlike generic tadalafil which requires a prescription. 

Avarante, whose active ingredient is tadalafil, belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. Here’s a simplified explanation of how it works:

1. 1. Blood Flow Regulation: When a man is sexually aroused, nitric oxide is released into the penis. This nitric oxide stimulates the production of cyclic guanosine monophosphate (cGMP), which is primarily responsible for controlling blood flow to the corpus cavernosum of the penis. The corpus cavernosum is the spongy tissue that fills with blood to produce an erection.
   2. PDE5 Inhibition: PDE5 is an enzyme found in the corpus cavernosum. It breaks down cGMP. Avarante works by inhibiting PDE5, which means that cGMP doesn’t get broken down as quickly. This leads to increased levels of cGMP in the corpus cavernosum.
   3. Enhanced Erection: With more cGMP present due to PDE5 inhibition by Avarante, the muscle cells in the walls of the blood vessels of the corpus cavernosum relax, allowing more blood to flow into the penis. This results in a firmer and longer-lasting erection.
   4. Duration: One of the distinctive features of Avarante, as compared to other PDE5 inhibitors, is its prolonged effect. This is why it’s sometimes referred to as the “weekend pill.” Depending on the dose and individual factors, its effects can last up to 36 hours.
   5. Limitations: It’s important to note that Avarante does not produce an erection on its own. Sexual arousal and stimulation are necessary for the drug to be effective. Additionally, it doesn’t offer protection against sexually transmitted infections, and it’s not a form of birth control.

For optimal use of Avarante Tablets, alike Tadalafil 1omg, adhere to the guidelines below:

Consume one tablet a minimum of 30 minutes prior to engaging in sexual activity. Limit yourself to a single tablet within a day’s span. Ingest the tablet without splitting, chewing, or grinding it. Use water to help swallow. To maximize the benefits of your treatment, keep these points in mind:

1. 1. Encourage Arousal: Note that Avarante isn’t an instant turn-on; it requires sexual stimulation to be effective. Participate in intimate moments and foreplay, as you normally would, even without the medication.
   2. Dietary Awareness: While you can take Avarante on an empty or full stomach, be aware that consuming it post a fatty meal might delay its effects.
   3. Ease Into It: If achieving an erection has been a challenge for a while, you might want to practice self-stimulation before engaging in partnered intimacy. This helps you reacquaint yourself with the sensation.
   4. Stay Hopeful: If you don’t see results after the first use, don’t get discouraged. Re-acclimating to regular erections might take a bit. However, refrain from exceeding one tablet daily. Overdosing won’t heighten its efficacy but may raise the likelihood of adverse reactions.
   5. Review the Guidelines: For a comprehensive understanding of your medication, refer to the accompanying Patient Information Leaflet. This will give you insights for ensuring the effectiveness of your treatment.

Avarante, which contains the active ingredient tadalafil, is primarily used for treating erectile dysfunction. Like all medications, it can have side effects. Here are some of the common side effects of Avarante:

1. 1. Headache: This is one of the most frequently reported side effects.
   2. Indigestion or heartburn.
   3. Back pain.
   4. Muscle aches: These can occur in the lower back, thighs, or legs and usually start 12 to 24 hours after taking the tablet. They often go away by themselves within 48 hours.
   5. Flushing: This can be noted as a warm feeling, redness, or tingly sensation on the skin.
   6. Stuffy or runny nose.
   7. Nausea.
   8. Dizziness.
   9. Vision changes: This can include blurry vision or seeing a blue tint. On rare occasions, it can cause a sudden loss of vision in one or both eyes, which could be a sign of a serious eye problem.
   10. Hearing loss: In some rare cases, Avarante has been linked to sudden hearing loss. 

It’s crucial to be aware of these side effects, and if they persist or become bothersome, it’s advised to seek medical attention. Furthermore, if you experience any severe side effects, such as chest pain, an erection that doesn’t go away after 4 hours (priapism), or significant vision and hearing problems, you should seek emergency medical care immediately.

For a complete list of side effects, please refer to the patient information leaflet for Avarante.

Avarante (tadalafil) can interact with several medications, potentially leading to unwanted side effects or reduced effectiveness. It’s crucial to inform your doctor about all the drugs you’re taking, including over-the-counter medicines, vitamins, and herbal products. Here are some of the key medications and substances that may interact with Avarante:

1. Nitrates: This includes drugs like nitroglycerin, isosorbide mononitrate, and isosorbide dinitrate. Combining Avarante with nitrates can result in a significant drop in blood pressure, which can be life-threatening.
2. Alpha-blockers: Used primarily for high blood pressure or prostate conditions, e.g., terazosin, tamsulosin, and doxazosin. Taking these with Avarante can lead to a notable decrease in blood pressure.
3. Other PDE5 inhibitors: Such as sildenafil (Viagra) or vardenafil (Levitra). Using these medications concurrently can result in an overdose.
4. Blood pressure medications: There’s a potential for an added blood pressure-lowering effect when combined with Avarante.
5. Antifungal medications: Such as ketoconazole or itraconazole, can increase the levels of Avarante in the blood, potentially leading to increased side effects.
6. Certain Antibiotics: Like erythromycin and clarithromycin can elevate Avarante levels in your blood, increasing the risk of side effects.
7. HIV protease inhibitors: Like ritonavir and saquinavir can also increase the levels of Avarante in the blood.
8. Antiseizure medications: Such as carbamazepine, phenytoin, and phenobarbital can decrease the effectiveness of Avarante.
9. Riociguat (Adempas): Used to treat pulmonary arterial hypertension, it can have its effects amplified by Avarante, leading to potential harmful drops in blood pressure.
10. Grapefruit and grapefruit juice: While not a medication, grapefruit products can increase the levels of many drugs, including Avarante, in the bloodstream, amplifying the risk of side effects.
11. Excessive alcohol consumption: Drinking large amounts of alcohol when taking Avarante can increase the potential for side effects such as dizziness, headache, fast heartbeat, and low blood pressure.

Yes.

Before purchasing Avarante, it’s essential to undergo an evaluation by a pharmacist. This evaluation can be completed either online or in-person at a pharmacy. If opting for the in-person route, scheduling an appointment might be necessary.

The Family Chemist’s pharmacy offers an online consultation for Avarante and other treatments for erectile dysfunction. This assessment encompasses detailed information about the condition and the treatments available. Once the online consultation concludes, individuals can select from a variety of erectile dysfunction medicines, including Avarante. Other options like Cialis, Viagra, Spedra, and their generic counterparts such as tadalafil, sildenafil, and vardenafil are available in different strengths and quantities.

Avarante is intended for men aged 18 and over who are experiencing symptoms of erectile dysfunction. It is not suitable for women or children.

Consuming alcohol can temporarily impair your ability to get an erection. To get the maximum benefit from Avarante, avoiding excessive drinking before taking it is advisable.